{"id":14600,"date":"2023-11-13T04:22:35","date_gmt":"2023-11-13T04:22:35","guid":{"rendered":"https:\/\/galenica.cl\/english\/?post_type=product&p=14600"},"modified":"2023-12-07T15:47:23","modified_gmt":"2023-12-07T15:47:23","slug":"verigene-enteric-pathogens-test","status":"publish","type":"product","link":"https:\/\/galenica.cl\/english\/product\/verigene-enteric-pathogens-test\/","title":{"rendered":"VERIGENE\u00ae Enteric Pathogens Test"},"content":{"rendered":"
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\nRapid molecular panel for detecting bacteria, viruses, and toxins that commonly cause acute diarrhea<\/p>\n

The VERIGENE\u00ae Enteric Pathogens Nucleic Acid Test (EP) is a multiplexed, qualitative test for simultaneous detection and identification of common pathogenic enteric bacteria, viruses, and genetic virulence markers from liquid or soft stool preserved in Cary-Blair medium, collected from individuals with signs and symptoms of gastrointestinal infection. The test is performed on the automated VERIGENE System utilizing reverse transcription (RT), polymerase chain reaction (PCR), and array hybridization to detect specific gastrointestinal microbial nucleic acid gene sequences associated with the following pathogenic bacteria and viruses: Campylobacter Group (composed of C. coli, C. jejuni, and C. lari), Salmonella species, Shigella species (including S. dysenteriae, S. boydii, S. sonnei, and S. flexneri), Vibrio Group (composed of V. cholerae and V. parahaemolyticus), Yersinia enterocolitica, Norovirus GI\/GII, Rotavirus A.<\/p>\n

In addition, EP detects the Shiga toxin 1 gene and Shiga toxin 2 gene virulence markers. Shiga toxin producing E. coli (STEC) typically harbor one or both genes that encode for Shiga toxins 1 and 2.<\/p>\n

EP is indicated as an aid in the diagnosis of specific agents of gastrointestinal illness, in conjunction with other clinical, laboratory, and epidemiological information; however, is not to be used to monitor these infections. EP also aids in the detection and identification of acute gastroenteritis in the context of outbreaks.<\/p>\n

Due to the limited number of positive specimens collected for certain organisms during the prospective clinical study, performance characteristics for Yersinia enterocolitica, Vibrio Group and Shigella species were primarily established with contrived specimens.<\/p>\n

Concomitant culture is necessary for organism recovery and further typing of bacterial agents.<\/p>\n

EP results should not be used as the sole basis for diagnosis, treatment, or other patient management decisions. Confirmed positive results do not rule out co-infection with other organisms that are not detected by this test, and may not be the sole or definitive cause of patient illness. Negative EP results in the setting of clinical illness compatible with gastroenteritis may be due to infection by pathogens that are not detected by this test or non-infectious causes such as ulcerative colitis, irritable bowel syndrome, or Crohn\u2019s disease.<\/p>\n

The VERIGENE\u00ae Enteric Pathogen (EP) Test is a rapid, easy-to-use, and cost-effective alternative to traditional stool diagnostics that delivers clinical, economic, and workflow benefits to hospitals and laboratories.<\/p>\n

Clinical Benefits:<\/p>\n

Therapeutic: Results can improve patient management decision making, thereby minimizing use of inappropriate or unnecessary drugs.
\nAccurate: Stool culture is less sensitive than molecular methods, with molecular testing detecting almost three times as many infections in the same set of samples.
\nPublic Health: Results can trigger outbreak investigations.
\nDiagnostic: Results can mitigate further unnecessary downstream testing.
\nPsychologic: Results can lead to earlier peace of mind for the patient and physician once the causative pathogen has been identified.
\nWorkflow Benefits:<\/p>\n

Nearly 95% of all stool samples are negative, yet still require similar hands-on time by the technologist (1\u20132 hours) and incubation time (72\u201396 hours) per sample as a positive sample.
\nConfirmation of a negative stool sample takes only two hours on the VERIGENE\u00ae System, allowing laboratories to reallocate technologist time to other priorities within the lab.
\nEconomic Benefits:<\/p>\n

Lower cost from reduced use of inappropriate or unnecessary antimicrobial or antiviral drugs.
\nPotential reduction in length of stay and length of isolation for patients in the hospital.
\nReduced cost of sample send-out to reference laboratories.
\nReallocation of technician time.
\nEnteric Pathogens Test Specifications:
\nBacteria:<\/p>\n

Campylobacter Group
\nSalmonella spp.
\nShigella spp.
\nVibrio Group
\nYersinia enterocolitica
\nToxins:<\/p>\n

Shiga Toxin 1 (stx1)
\nShiga Toxin 2 (stx2)
\nViruses:<\/p>\n

Norovirus
\nRotavirus
\nFeatures:<\/p>\n

Automation: Sample-to-result
\nInstrumentation: VERIGENE\u00ae Reader and Processor SP
\nWorkflow: On-demand and scalable
\nSample Type: Stool preserved in cary-blair
\nPipetting Steps: One
\nHands-On Time: <5 minutes
\nRun Time: <2 hours<\/p>\n<\/div>\n<\/div><\/div>\n<\/div>\n<\/div>\n<\/div>\n<\/div>\n<\/div>\n\n","protected":false},"excerpt":{"rendered":"

Rapid molecular panel for detecting bacteria, viruses, and toxins that commonly cause acute diarrhea.<\/p>\n