Description
Laser Microdissection (LMD, also known as Laser Capture Microdissection or LCM) enables users to isolate specific single cells or entire areas of tissue. Powered by a unique laser design and dynamic software, Leica LMD systems allow users to easily isolate Regions of Interest (ROI) from entire areas of tissue down to single cells or even subcellular structures such as chromosomes.
LMD is typically used in genomics (DNA), transcriptomics (mRNA, miRNA), proteomics, metabolomics, and even next generation sequencing (NGS). Researchers in neurology, cancer research, plant analysis, forensics or climate research rely on this method. Furthermore, LMD is a perfect tool for live cell culture (LCC), for cloning and re-cultivation, manipulation or downstream analysis.
We move the laser, not the sample. And we use gravity for collection. That is why our LMD systems provide you with perfectly cut, contamination-free, analysis-ready dissectates.
Only Leica Microsystems uses high-precision optics to steer the laser beam along the desired cut line on the tissue with prisms. That means that the Leica LMD cuts perpendicularly to the tissue and leaves clean cuts of contamination-free isolates.
Cut with highest possible precision and speed
Cut directly, real-time with “Move and Cut”
Choose your system: The difference between the Leica LMD6 and Leica LMD7 is the laser. The LMD7 provides higher laser power and more laser controls than the LMD6
This makes the Leica LMD6 the tool for standard applications dissecting soft tissues such as brain, liver, or kidney. And it makes the Leica LMD7 ideally suited to dissect any kind of tissue independent of its size or shape.
Two systems for your discoveries Leica LMD6 for standard tissue dissection Leica LMD7 for higher laser power and more flexibility
The Leica LMD software is an intutive application software designed to streamline the process of selecting settings so that you can focus on obtaining high-quality regions of your sample.
LMD objectives are designed for the task of enabling flexible laser settings for unique applications. Leica’s development and manufacturing of optics has been among of our core competencies from the start in the 19th century, so you can rely on the performance of our dedicated LMD objectives.
Choose from a range of dry objectives – from 2.5x to 150x
Use the 150x SmartCut objective to go into detail with high magnification when required
Get a large field of view to cut large parts of samples in one piece with low-magnification objectives
Benefit from objectives with the highest possible transmission of laser light at 350 nm to cut tissue, bones, teeth, brain, plants, chromosomes and living cells.
The LMD6 and LMD7 systems can be combined with THUNDER. The base stand of the THUNDER Imager 3D Tissue and LMD systems are the same, thus such a combination offers:
Lab space savings with one system for different tasks
Laser Microdissection with the LMD without limitation
Brilliant THUNDER fluorescence imaging using LAS X, even in multi-color and 3D (z-stacks) and visualization in the 3D viewer.
